SAB4301399

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: DLP1, DNM1L, DRP1, DVLP, Dymple
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: 82 kDa
• reactividad de especies: human
• concentración: 1.0 mg/mL
• técnicas: western blot: 1:500-1:1000 (Cell Lysate)
• isotipo: IgG
• nº de acceso: NP_036192.2.
• Nº de acceso UniProt: O00429
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer637)
• Información sobre el gen: human ... DNM1L(10059)

Descripción

Descripción general

Dynamin related protein 1 (DRP1) is a dynamin-related guanosine triphosphatase. The gene is located on human chromosome 12p11.21. DRP1 is a cytosolic protein, which is also present on the outer mitochondrial membrane.

Especificidad

The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.

Inmunógeno

Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.

Aplicación

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit has been used in immunoblotting and western blotting.

Acciones bioquímicas o fisiológicas

Dynamin related protein 1 (DRP1) is an important regulator of mitochondrial fission and peroxisomal division. It regulates proper mitochondrial function, apoptosis and necrosis. Mutations in this gene is associated with Alzheimer′s disease.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable