SAB2106753

Anti-GOLIM4 antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 75 kDa
• species reactivity: dog, rabbit, mouse, human, horse, rat, bovine, guinea pig
• concentration: 0.5 mg - 1 mg/mL
• technique(s): western blot: suitable
• NCBI accession no.: NM_001191567
• UniProt accession no.: O00461
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... GOLIM4(27333) ; rat ... Golim4(310526)

Descripción

General description

Golgi internal membrane protein 4 (GOLIM4) is a golgi type II transmembrane phosphoprotein. In human chromosome, the gene GOLIM4 is located on 3q26.2.

Immunogen

The immunogen for anti-GOLIM4 antibody: synthetic peptide derected towards the C terminal of human GOLIM4

Biochem/physiol Actions

Golim4 plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi. Golim4 plays a major role in maintaining manganese homeostasis. The expression level of Golim4 is less in cancer cells. GOLIM4 is a potential oncogene, regulates cell cycle and apoptosis in neck and cancer cells.

Sequence

Synthetic peptide located within the following region: DPGNRQEFHEPGHQEGDPEAEADRAAAQDINPADDPNNQGEDEFEEAEQV

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable