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Merck

M2514

Sigma-Aldrich

4-Methylumbelliferyl heptanoate

≥95% (GC)

Sinónimos:

4-Methylumbelliferyl enanthate, Heptanoic acid 4-methylumbelliferyl ester

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About This Item

Fórmula empírica (notación de Hill):
C17H20O4
Número de CAS:
Peso molecular:
288.34
Beilstein:
1256801
Número CE:
Número MDL:
Código UNSPSC:
12352106
ID de la sustancia en PubChem:
NACRES:
NA.32
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Nivel de calidad

Ensayo

≥95% (GC)

Formulario

powder

mp

41-42 °C (lit.)

solubilidad

pyridine: 50 mg/mL, clear, colorless to faintly yellow

fluorescencia

λex 312 nm in methanol
λex 360 nm; λem 449 nm (Reaction product)

temp. de almacenamiento

−20°C

cadena SMILES

CCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C17H20O4/c1-3-4-5-6-7-16(18)20-13-8-9-14-12(2)10-17(19)21-15(14)11-13/h8-11H,3-7H2,1-2H3

Clave InChI

FFNBFZWIBOIPIV-UHFFFAOYSA-N

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Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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S Krüger-Krasagakes et al.
Journal of immunological methods, 156(1), 1-8 (1992-11-25)
In order to measure cell mediated cytotoxicity to adherent growing cell lines in vitro more rapidly and conveniently, a fluorometric microassay was developed and results were compared with those obtained by the 51Cr release assay. The fluorometric method is based
L Fiksdal et al.
Applied and environmental microbiology, 55(9), 2424-2427 (1989-09-01)
The production of an enzyme, 4-methylumbelliferyl heptanoate hydrolase, in Escherichia coli exposed to enriched and nonenriched seawater was studied. In all media, except for seawater with no or very small amounts of organic material and seawater enriched with peptone, 4-methylumbelliferyl
L Virág et al.
Journal of immunological methods, 185(2), 199-208 (1995-09-25)
A fluorimetric method using 4-methylumbelliferyl heptanoate (MUH) has been developed for detecting cell-mediated cytotoxicity and cell proliferation. The assay is based on the hydrolysis of the fluorochrome (MUH) by intracellular esterases of viable cells resulting in the production of highly
E N Dotsika et al.
Journal of immunological methods, 105(1), 55-62 (1987-12-04)
A microplate method for assessing cell growth and viability based on the hydrolysis of fluorogenic substrates by cell esterases has been investigated. Living cells incubated with fluorescein diacetate or 4-methylumbelliferyl heptanoate generate a fluorescent product which is proportional to the
C C Zouboulis et al.
Melanoma research, 1(2), 91-95 (1991-06-01)
A simple, rapid and reproducible assay for the determination of melanoma cell proliferation in vitro is described, based on the hydrolysis of a fluorogenic substrate by cell esterases in the cytoplasm of living cells. Human melanoma cells were cultured at

Questions

  1. If a lab cannot store this chemical at -20C. will the product still be stable to run for lipase assay using fluorescence spectrometer?

    1 answer
    1. The optimum storage temperature for this compound is -20 deg. C. The product is shipped at ambient temperature and is stable for relatively short periods of time outside of the recommended storage conditions. One to two weeks are typically allowed for transit time. The long term stability of the product at ambient temperature has not been established and the integrity of the product may be compromised.

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