M1520
IgM, Kappa from murine myeloma
clone TEPC 183, ascites fluid, lyophilized powder
Sinónimos:
Mouse IgM-κ
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About This Item
Productos recomendados
origen biológico
mouse
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
ascites fluid
clon
TEPC 183, monoclonal
Formulario
lyophilized powder
temp. de almacenamiento
2-8°C
modificación del objetivo postraduccional
unmodified
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Descripción general
The TEPC-183 tumor line that produces mouse IgM is a tetramethylpentadecane (pristane) induced plasmacytoma, originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.
Aplicación
IgM, Kappa from murine myeloma has been used as a control to study its effects on brain derived synaptic plasticity.
Acciones bioquímicas o fisiológicas
IgM antibodies are present as pentamers in serum and are produced in response to antigens.
Reconstitución
Reconstitute with 1 ml deionized water.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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M Lohoff et al.
Infection and immunity, 56(8), 2120-2124 (1988-08-01)
The well-established polyclonal B-cell stimulation in the lymphoid organs in mice infected with Leishmania major is thought to be dependent on T cells. Here we present clear experimental evidence that this is indeed the case by showing that BALB/c-derived, L3T4-positive
Molecular Genetics of Immunoglobulin, 17 (1987)
A monoclonal antibody against synthetic A beta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting A beta
ONuallain B, et al.
Journal of Neurochemistry, 119(1), 189-201 (2011)
Brian O'Nuallain et al.
Journal of neurochemistry, 119(1), 189-201 (2011-07-26)
Diverse lines of evidence indicate that pre-fibrillar, diffusible assemblies of the amyloid β-protein (Aβ) play an important role in Alzheimer's disease pathogenesis. Although the precise molecular identity of these soluble toxins remains unsettled, recent experiments suggest that sodium dodecyl sulfate
The Immunoglobulins: Structure and Function (1998)
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