M0938
7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(DNP)-D-Arg-amide
>97% (HPLC), solid
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About This Item
Fórmula empírica (notación de Hill):
C85H122N22O19
Peso molecular:
1756.01
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32
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Quality Level
assay
>97% (HPLC)
form
solid
storage temp.
−20°C
Gene Information
human ... CTSD(1509) , CTSE(1510)
mouse ... CTSD(13033) , CTSE(13034)
rat ... CTSD(171293) , CTSE(25424)
Amino Acid Sequence
MCA-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-DNP-Arg-NH2
Application
7-methoxycoumarin-4-acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(DNP)-DArg-amide has been used as a fluorogenic substrate for the quantification of cathepsin D in decapod crustaceans.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Substrates
Substrate for cathepsin D and E.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Cold-adapted digestive aspartic protease of the clawed lobsters Homarus americanus and Homarus gammarus: biochemical characterization
Liliana Rojo
Marine Biotechnology (2013)
Is digestive cathepsin D the rule in decapod crustaceans?
Martinez A D, et al.
Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology, 215, 31-38 (2018)
Multiple effects of pepstatin A on Trypanosoma cruzi epimastigote forms.
Sangenito LS
Parasitology Research (2012)
Diana Martínez-Alarcón et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 215, 31-38 (2017-10-17)
Cathepsin D is an aspartic endopetidase with typical characteristics of lysosomal enzymes. Cathepsin D activity has been reported in the gastric fluid of clawed lobsters where it acts as an extracellular digestive enzyme. Here we investigate whether cathepsin D is
Bianca Santos Henriques et al.
Frontiers in physiology, 11, 509310-509310 (2021-02-02)
Rhodnius prolixus is one important vector for the parasite Trypanosoma cruzi in Latin America, where Chagas disease is a significant health issue. Although R. prolixus is a model for investigations of vector-parasite interaction and transmission, not much has been done
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