I2018

Monoclonal Anti-Insulin antibody produced in mouse

clone K36AC10, ascites fluid

• Sinónimos: Insulin Antibody, Insulin Antibody - Monoclonal Anti-Insulin antibody produced in mouse
• Número MDL: MFCD00164675
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: ascites fluid
• tipo de anticuerpo: primary antibodies
• clon: K36AC10, monoclonal
• contiene: 15 mM sodium azide
• reactividad de especies: feline, human, rat, horse, rabbit, guinea pig, bovine, monkey, sheep, canine, pig
• técnicas: dot blot: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using human or animal pancreas; radioimmunoassay: suitable
• isotipo: IgG1
• Nº de acceso UniProt: P01308
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... INS(3630)

Descripción

Descripción general

The antibody reacts specifically against insulin by RIA and immunocytochemistry. It exhibits cross-reactivity with human proinsulin. The antibody binds to insulin with an affinity constant of 8.8 × 10⁹ M^-1 in RIA.

The insulin gene is mapped to human chromosome 11p15.5.

Aplicación

Monoclonal Anti-Insulin antibody produced in mouse has been used in immunoblotting assay and ELISA.

Monoclonal Anti-Insulin antibody produced in mouse was used in ELISA-based protein pin array assay to study the interactions between human αB crystalline and insulin. It was used for flow cytometric analysis of rat white blood cells and mast cells.

Acciones bioquímicas o fisiológicas

Insulin is a major regulatory hormone important in the metabolic processes, transport of glucose, amino acids and certain ions. It is also involved in the synthesis of nucleic acids and proteins. The biological effects of insulin are mediated by insulin receptor and it integrates multiple major signaling pathways.

Insulin is a major regulatory hormone important in the metabolic processes, transport of glucose, amino acids and certain ions. It is also involved in the synthesis of nucleic acids and proteins. The biological effects of insulin are mediated by insulin receptor and it integrates multiple major signaling pathways. Abnormal insulin secretion or function leads to diabetes mellitus, obesity and other carbohydrate metabolism disorders. Insulin is known to stimulate cell division.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable