I117

R(+)-IAA-94

≥98% (HPLC), solid

• Sinónimos: Indanyloxyacetic acid 94, R(+)-Methylindazone, R(+)-[(6,7-Dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy]acetic acid
• Fórmula empírica (notación de Hill): C₁₇H₁₈Cl₂O₄
• Número de CAS: 54197-31-8
• Peso molecular: 357.23
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277844
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• optical activity: [α]22/D +36.4°, c = 0.86 in methanol(lit.)
• color: white
• solubility: H₂O: 0.2 mg/mL; 0.1 M NaOH: 2.8 mg/mL; DMSO: >20 mg/mL; ethanol: 20 mg/mL; dilute aqueous acid: insoluble
• storage temp.: 2-8°C
• SMILES string: C[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3
• InChI: 1S/C17H18Cl2O4/c1-17(10-4-2-3-5-10)7-9-6-11(23-8-12(20)21)14(18)15(19)13(9)16(17)22/h6,10H,2-5,7-8H2,1H3,(H,20,21)/t17-/m1/s1
• InChI key: RNOJGTHBMJBOSP-QGZVFWFLSA-N

Descripción

Application

R(+)-IAA-94 has been used as a chloride ion channel inhibitor to study its effects on grepafloxacin uptake by human mononuclear (THP-1) cells . It has also been used as a chloride ion channel inhibitor to study its effects on moxifloxacin uptake by human mononuclear (THP-1) cells.

Features and Benefits

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)