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G2262

Sigma-Aldrich

γ-Glutamyltranspeptidase from porcine kidney

Type IV, 2.0-6.0 units/mg solid

Sinónimos:

γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP

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About This Item

Número de CAS:
9046-27-9
Comisión internacional de enzimas:
2.3.2.2 (BRENDA, IUBMB)
EC Number:
232-931-5
MDL number:
MFCD00131126
UNSPSC Code:
12352204
NACRES:
NA.54

type

Type IV

Quality Level

200

form

powder

specific activity

2.0-6.0 units/mg solid

storage temp.

−20°C

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Application

γ-Glutamyltranspeptidase is used in the food industry to improve the umami taste of soy sauce.

Biochem/physiol Actions

γ- Glutamyltranspeptidase cleaves theγ-glutamyl amide bond from glutathione and its S-conjugates to remove glutamate.

Quality

Crude

Unit Definition

One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.

inhibitor

Referencia del producto
Descripción
Precios

I2512

Sodium iodoacetate, ≥98%

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Improving the umami taste of soy sauce by the addition of bacterial γ-glutamyltranspeptidase as a glutaminase to the fermentation mixture
K. Kijima & H. Suzuki
Enzyme and Microbial Technology, 41, 80-84 (2007)
S S Tate et al.
Molecular and cellular biochemistry, 39, 357-368 (1981-09-25)
gamma-Glutamyl transpeptidase catalyzes transfer of the gamma-glutamyl moiety of glutathione to amino acids, dipeptides, and to glutathione itself; the enzyme also catalyzes the hydrolysis of glutathione to glutamate and cysteinyl-glycine. This review deals with the tissue distribution and localization of
R Foddis et al.
Giornale italiano di medicina del lavoro ed ergonomia, 34(3 Suppl), 565-567 (2013-02-15)
The GGT enzyme, considered for years only as a marker of liver disease and alcohol abuse, has now revealed a risk of death for many causes. Through a molecular exclusion chromatography on FPLC system (Fast Protein Liquid Chromatography), it is
Mathias Oertli et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(8), 3047-3052 (2013-02-06)
Infection with the gastric bacterial pathogen Helicobacter pylori is typically contracted in early childhood and often persists for decades. The immunomodulatory properties of H. pylori that allow it to colonize humans persistently are believed to also account for H. pylori's
Stephanie Wickham et al.
The Biochemical journal, 450(3), 547-557 (2013-01-11)
GGT (γ-glutamyl transpeptidase) is an essential enzyme for maintaining cysteine homoeostasis, leukotriene synthesis, metabolism of glutathione conjugates and catabolism of extracellular glutathione. Overexpression of GGT has been implicated in many pathologies, and clinical inhibitors of GGT are under development for
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