G1639

D-(+)-Galactosamine hydrochloride

BioReagent, suitable for cell culture

• Sinónimos: 2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride
• Fórmula empírica (notación de Hill): C₆H₁₃NO₅ · HCl
• Número de CAS: 1772-03-8
• Peso molecular: 215.63
• Beilstein/REAXYS Number: 3697825
• EC Number: 217-198-1
• MDL number: MFCD00135830
• UNSPSC Code: 12352209
• PubChem Substance ID: 24895072
• NACRES: NA.75

Propiedades

• biological source: fish cartilage (shark)
• Quality Level: 200
• product line: BioReagent
• assay: ≥99%
• technique(s): cell culture | mammalian: suitable
• impurities: Glucosamine, essentially free
• solubility: water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO
• InChI: 1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1
• InChI key: CBOJBBMQJBVCMW-NQZVPSPJSA-N

Descripción

Application

D-(+)-Galactosamine hydrochloride has been used to:

• induce livery injury
• inflammatory liver injury
• acute liver failure (ALF) in mice

Biochem/physiol Actions

Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF).

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)