F5392
Fibroblast Growth Factor-Basic from bovine pituitary
~90% (SDS-PAGE and N-terminal analysis), lyophilized powder, suitable for cell culture
Sinónimos:
FGF2, bFGF
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About This Item
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Nombre del producto
Fibroblast Growth Factor-Basic from bovine pituitary, FGF-Basic, suitable for cell culture
origen biológico
bovine pituitary glands
Nivel de calidad
Ensayo
~90% (SDS-PAGE and N-terminal analysis)
Formulario
lyophilized powder
potencia
0.03-3.0 ng/mL ED50/EC50
calidad
endotoxin tested
mol peso
16.4 kDa
envase
pkg of 1 μg
condiciones de almacenamiento
avoid repeated freeze/thaw cycles
técnicas
cell culture | mammalian: suitable
impurezas
<0.5 EU/vial
color
white
Nº de acceso UniProt
temp. de almacenamiento
−20°C
Información sobre el gen
bovine ... FGF2(281161)
Descripción general
The fibroblast growth factor-2 (FGF2) gene is predominantly expressed in uterus, cornea and vascular endothelial cells. The FGF2 gene is mapped to cattle chromosome 17.
Aplicación
A natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.
Fibroblast Growth Factor-Basic from bovine pituitary has been used:
Fibroblast Growth Factor-Basic from bovine pituitary has been used:
- In animal and human cell culture
- In neuronal induction of adipose and bone marrow-derived rat mesenchymal stem cells
- In the generation of directly reprogramming fibroblast
- In human glioma cell culture
Acciones bioquímicas o fisiológicas
Fibroblast growth factor-2 (FGF2) stimulates cell proliferation, differentiation and migration. It is also known to participate in angiogenesis and carcinogenesis. During the estrous cycle, FGF2 expression is found to be maximum in porcine conceptuses and endometrium. Upregulation of this gene is also observed in pregnancy during peri-implantation. FGF2 is involved in embryogenesis, tissue repair and other metabolic pathways.
Forma física
Lyophilized from a 0.2 μm filtered solution in sodium phosphate and sodium chloride containing 0.1 mg bovine serum albumin
Nota de preparación
Purified glands by a modification of the method of Gospodarowicz, et al.
Nota de análisis
The proliferative activity is tested in culture using fetal bovine heart endothelial cells.
Producto relacionado
Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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