C9538

Coenzyme Q₁₀

≥98% (HPLC), powder, antioxidant

• Sinónimos: CoQ10, Q-10, Ubiquinone 50, Ubiquinone-10
• Fórmula empírica (notación de Hill): C₅₉H₉₀O₄
• Número de CAS: 303-98-0
• Peso molecular: 863.34
• Beilstein: 1900141
• Número CE: 206-147-9
• Número MDL: MFCD00042919
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24893170
• NACRES: NA.77

Propiedades

• Nombre del producto: Coenzyme Q₁₀, ≥98% (HPLC)
• Nivel de calidad: 200
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: yellow to dark orange
• mp: 49 °C
• aplicaciones: cell analysis
• temp. de almacenamiento: −20°C
• cadena SMILES: O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O
• InChI: 1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
• Clave InChI: ACTIUHUUMQJHFO-UPTCCGCDSA-N

Descripción

Descripción general

Coenzyme Q (CoQ), also known as ubiquinone, is a lipid-soluble antioxidant and is an essential component of the mitochondrial electron transport chain. The molecule contains a biologically active quinone with a benzoquinone ring and an isoprenoid sidechain. Q10 is synthesized in the cytoplasm and mitochondria () which generates ATP through aerobic cellular respiration. CoQ10 is required for the optimal functioning of the immune system and for cardiovascular health (). The ability to repress inflammatory gene expression exhibits its anti-inflammatory property ( ) Genetic failure or ageing results in CoQ10 deficiency, indicated by suppression of immune function. ()

Aplicación

Coenzyme Q10 (CoQ10) has been used:

• as a bioactive compound to study its immune modulating properties in vitro
• as a standard for high-performance liquid chromatography
• to study its effect on exercised rat aorta
• in the cellular CoQ uptake assay

Acciones bioquímicas o fisiológicas

Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)