C7017

Cloruro de colina

≥99%

• Sinónimos: Cloruro de (2-hidroxietil)trimetilamonio
• Fórmula lineal: (CH₃)₃N(Cl)CH₂CH₂OH
• Número de CAS: 67-48-1
• Peso molecular: 139.62
• Beilstein: 3563126
• Número CE: 200-655-4
• Número MDL: MFCD00011721
• Código UNSPSC: 50501514
• ID de la sustancia en PubChem: 57654039
• NACRES: NA.25

Propiedades

• origen biológico: synthetic
• Nivel de calidad: 200
• Ensayo: ≥99%
• Formulario: powder
• color: white
• mp: 302-305 °C (dec.) (lit.)
• tipo de lípido: phospholipids
• cadena SMILES: [Cl-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
• Clave InChI: SGMZJAMFUVOLNK-UHFFFAOYSA-M

Descripción

Descripción general

Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.

Aplicación

Choline chloride has been used:

• in choline release assay
• as an endogenous agonist of sigma-1 receptors (Sig-1Rs)
• as a standard to analyse interrelationships between methionine and choline metabolism

Acciones bioquímicas o fisiológicas

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Sustratos

Sustrato de la colina acetiltransferasa

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves