C0289

Cholesteryl linoleate

≥98% (HPLC; detection at 205 nm)

• Sinónimos: 3β-Hydroxy-5-cholestene 3-linoleate, 5-Cholesten-3β-ol 3-linoleate, Cholesteryl 9,12-octadecadienoate, Cholesteryl octadecadienoate
• Fórmula empírica (notación de Hill): C₄₅H₇₆O₂
• Número de CAS: 604-33-1
• Peso molecular: 649.08
• Número CE: 210-065-9
• Número MDL: MFCD00003644
• Código UNSPSC: 12352211
• ID de la sustancia en PubChem: 24892247
• NACRES: NA.77

Propiedades

• origen biológico: synthetic (organic)
• Nivel de calidad: 200
• Ensayo: ≥98% (HPLC; detection at 205 nm)
• Formulario: powder
• grupo funcional: ester
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: CCCCC\C=C/C\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCCC(C)C
• InChI: 1S/C45H76O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44/h11-12,14-15,26,35-36,38-42H,7-10,13,16-25,27-34H2,1-6H3/b12-11-,15-14-/t36-,38+,39+,40-,41+,42+,44+,45-/m1/s1
• Clave InChI: NAACPBBQTFFYQB-LJAITQKLSA-N

Descripción

Aplicación

Cholesteryl linoleate was cosonicated with cholesterol to prepare dispersions were prepared to study the cholesterol to phospholipid ratio in red blood cell membrane. It was used as HPLC standard in the analysis of rat liver lipoproteins.

Acciones bioquímicas o fisiológicas

Cholesteryl linoleate is a major cholesterol ester found associated with the neutral core of low density lipoprotein. Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters. The enzyme acid cholesteryl ester hydrolase is responsible for the hydrolysis of cholesteryl esters; a defective enzyme can result in the formation of atherosclerotic lesions in humans.

The most abundant cholesteryl ester in low density lipoprotein (LDL).

Envase

Sealed ampule

Nota de preparación

Cholesteryl linoleate yields clear, colorless solution in chloroform at 100 mg/ml.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)