B5556
Bay 11-7082
≥98% (HPLC), powder, NF-kB/TNF-α inhibitor
Sinónimos:
(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile
About This Item
Productos recomendados
product name
Bay 11-7082, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: >20 mg/mL
H2O: insoluble
SMILES string
Cc1ccc(cc1)S(=O)(=O)\C=C\C#N
InChI
1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+
InChI key
DOEWDSDBFRHVAP-KRXBUXKQSA-N
1 of 4
Este artículo | B5681 | SML2817 | SML0607 |
---|---|---|---|
powder | solid | powder | powder |
100 | 100 | 100 | - |
DMSO: >20 mg/mL, H2O: insoluble | DMSO: soluble >25 mg/mL, H2O: insoluble | DMSO: 2 mg/mL, clear | DMSO: 20 mg/mL, clear |
white | white | white to beige | white to beige |
Application
- a nuclear factor-kappa B (NF-kB) inhibitor to verify the action of the NF-kB signaling pathway in the production of interleukin (IL)-8[1]
- a nuclear factor-kappa B (NF-kB) inhibitor to study the role of NF-kB activation in Mycoplasma hyorhinis -induced epithelial-mesenchymal transition (EMT) and cell migration[2]
- a nod-like receptor family pyrin domain containing 3 (NLRP3) selective inhibitor to examine its effects on liver inflammation in mice after hematopoietic stem cell transplantation[3]
Biochem/physiol Actions
Features and Benefits
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Artículos
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
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