B2643

Biotinamidohexanoic acid N-hydroxysuccinimide ester

≥98% (TLC), powder

• Sinónimos: (+)-Biotinamidocaproate N-hydroxysuccinimidyl ester, N-(+)-Biotinyl-6-aminocaproic acid N-succinimidyl ester, N-(+)-Biotinyl-6-aminohexanoic acid NHS ester, N-Succinimidyl N-biotinyl-6-aminocaproate, Succinimidyl 6-(biotinamido)hexanoate
• Fórmula empírica (notación de Hill): C₂₀H₃₀N₄O₆S
• Número de CAS: 72040-63-2
• Peso molecular: 454.54
• Beilstein: 3577403
• Número MDL: MFCD00065502
• Código UNSPSC: 12352203
• ID de la sustancia en PubChem: 24891665
• NACRES: NA.46

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98% (TLC)
• Formulario: powder
• solubilidad: H₂O: ≤2 mg/mL (with sonication); DMF: 50 mg/mL (Stable up to 2 months in dry DMF.)
• temp. de almacenamiento: −20°C
• cadena SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1
• Clave InChI: UVGHPGOONBRLCX-NJSLBKSFSA-N

Descripción

Aplicación

Biotinamidohexanoic acid N-hydroxysuccinimide ester has been used in the biotinylation of antibodies.

Acciones bioquímicas o fisiológicas

Biotin is a label widely used in several biochemical applications and has a high affinity for avidin. A spacer chain is required to reduce steric hindrance while coupling biotin (a small molecule) to biopolymers (large molecules). Biotinamidohexanoic acid N-hydroxysuccinimide ester incorporates a 7-atom spacer with the N-succinimide leaving group. It can react with a primary amine in the pH range of 6.5-8.5. This biotinylation reagent incorporates an aminocaproyl spacer and thus can reduce the steric hindrance in binding avidin to some biotinylated compounds.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)