A9376

Adenosine 2′:3′-cyclic monophosphate sodium salt

≥93%

• Sinónimos: 2′,3′-cAMP sodium salt
• Fórmula lineal: C₁₀H₁₁N₅O₆PNa
• Número de CAS: 37063-35-7
• Peso molecular: 351.19
• Número CE: 253-328-3
• Número MDL: MFCD00005757
• Código UNSPSC: 41106305
• eCl@ss: 32160414
• ID de la sustancia en PubChem: 24891439
• NACRES: NA.51

Propiedades

• origen biológico: synthetic (organic)
• Nivel de calidad: 200
• Ensayo: ≥93%
• Formulario: powder
• solubilidad: water: 50 mg/mL, clear, colorless
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H]4OP([O-])(=O)O[C@@H]34
• InChI: 1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(4(1-16)19-10)20-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• Clave InChI: VSDSIACSNXHGOV-MCDZGGTQSA-M

Descripción

Aplicación

Adenosine 2′:3′-cyclic monophosphate sodium salt has been used in lysis buffer for affinity purification and also in microscale thermophoresis measurements. It has also been used in electrophysiological studies of Tenebrio tubules.

Acciones bioquímicas o fisiológicas

Adenosine 2′,3′-cyclic monophosphate (2′,3′-cAMP) is believed to serve as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.

Precaución

Caution: Do not confuse with the common adenosine 2′(3′)-monophosphate (mixed isomers).

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable