A7470
Anti-c-Myc
affinity isolated antibody
Sinónimos:
Anti-c-Myc
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.56
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origen biológico
rabbit
Nivel de calidad
conjugado
agarose conjugate
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
primary antibodies
clon
polyclonal
reactividad de especies
human
clases químicas de analitos
proteins (c-Myc)
técnicas
affinity chromatography: suitable
immunoprecipitation (IP): suitable
capacidad
≥10 nmol/mL binding capacity (c-Myc tagged fusion protein)
≥7 nmol/mL elution capacity (c-Myc tagged fusion protein)
Nº de acceso UniProt
temp. de almacenamiento
2-8°C
Información sobre el gen
human ... MYC(4609)
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Descripción general
The human c-Myc proto-oncogene belongs to MYC oncogene family and is the human cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses. c-Myc gene is localized on human chromosome 8q24.21. The two major domains of include the N-terminal box regions and the C-terminal basic-region with helix-loop-helix/leucine-zipper motif.
Especificidad
Anti-c-Myc recognizes an epitope located on c-Myc tagged fusion proteins.
Inmunógeno
péptido sintético de la proteína p62c-Myc humana.
Aplicación
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit has been used in:
- chromatin immunoprecipitation (ChIP)
- co-immunoprecipitation
- western blotting
- immunofluorescence
- immunoprecipitation
Acciones bioquímicas o fisiológicas
c-Myc proto-oncogene increased expression is observed in a variety of human tumors. Amplification of Myc gene locus is observed in angiosarcomas and translocation is implicated in Burkitt′s lymphoma. c-Myc is a master regulator and targets a wide variety of metabolic events. An epitope located within amino acid residues 410-419 (EQKLISEEDL) of human c-Myc has been widely used as a tag in many expression vectors, enabling the expression of proteins as c-Myc tagged fusion proteins. Anti-c-Myc agarose is useful in the purification of expressed c-Myc tagged fusion proteins in bacterial lysates or transfected cells.
Forma física
Suspension of beaded agarose (1:1 v/v) in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
Almacenamiento y estabilidad
For continuous use and extended storage, store at 2 °C to 8 °C. Do not freeze.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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