A5855

Abz-LFK(Dnp)-OH trifluoroacetate salt

≥97% (HPLC)

• Sinónimos: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt
• Fórmula empírica (notación de Hill): C₃₄H₄₁N₇O₉ · xC₂HF₃O₂
• Peso molecular: 691.73 (free base basis)
• MDL number: MFCD11045275
• UNSPSC Code: 12352200
• PubChem Substance ID: 329770877
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥97% (HPLC)
• form: film
• color: yellow
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)c1ccccc1N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCNc3ccc(cc3[N+]([O-])=O)[N+]([O-])=O)C(O)=O
• InChI: 1S/C34H41N7O9.C2HF3O2/c1-21(2)18-28(38-31(42)24-12-6-7-13-25(24)35)32(43)39-29(19-22-10-4-3-5-11-22)33(44)37-27(34(45)46)14-8-9-17-36-26-16-15-23(40(47)48)20-30(26)41(49)50;3-2(4,5)1(6)7/h3-7,10-13,15-16,20-21,27-29,36H,8-9,14,17-19,35H2,1-2H3,(H,37,44)(H,38,42)(H,39,43)(H,45,46);(H,6,7)/t27-,28-,29-;/m0./s1
• InChI key: BAXBDLHYKKDHEJ-BJRQXHFHSA-N

Descripción

Amino Acid Sequence

Abz-Leu-Phe-Lys-DNP

Application

Abz-LFK(Dnp)-OH trifluoroacetate (TFA) salt is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. Abz-LFK(Dnp)-OH TFA has been used to study the development of new antibacterial calixarene derivatives, as well as the efficacy and toxicity of the antimicrobial peptide M33 as a possible antimicrobial agent in lung infections and sepsis.

Biochem/physiol Actions

Abz-LFK(Dnp)-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the C domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable