51290

Hemoglobin from bovine blood

lyophilized, 2×cryst., ≥90% (SDS-PAGE), powder

• Sinónimos: Bovine hemoglobin, Hb, Methemoglobin
• Número de CAS: 9008-02-0
• Número MDL: MFCD00131282
• Código UNSPSC: 12352202

Propiedades

• origen biológico: bovine blood
• Nivel de calidad: 100
• Ensayo: ≥90% (SDS-PAGE)
• Formulario: powder
• calidad: 2×cryst.; lyophilized
• mol peso: M_r ~64500
• técnicas: UV/Vis spectroscopy: suitable
• impurezas: salt, none detected; ~0.3% Fe
• pérdida: ≤8% loss on drying
• Nº de acceso UniProt: P01966; P02070; P02081; P06642; P06643
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)

Descripción

Descripción general

Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.

Aplicación

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Acciones bioquímicas o fisiológicas

Oxygen transporter, NO scavenger

Oxygen transporter. The Fe²⁺/Fe³⁺ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Precaución

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Otras notas

Review: Oxygen carrier proteins

Sales restrictions may apply

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)