45124
Elastase from porcine pancreas
powder, white, ≥10 U/mg
Sinónimos:
Elastase from hog pancreas, Pancreatopeptidase E
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About This Item
Productos recomendados
biological source
Porcine pancreas
form
powder
specific activity
≥10 U/mg
mol wt
Mr ~25000
color
white
storage temp.
−20°C
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Biochem/physiol Actions
Elastase hydrolyses elastin, the specific protein of elastic fibers, and digests hemoglobin, casein and fibrin.
Unit Definition
1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)
One unit will hydrolyze 1.0 μmole of N-succinyl-L-Ala-Ala-Ala-p-nitroanilide per min, pH 8.0 at 25 °C.
Other Notes
Cleaves polyalanyl-lysine peptides at the alanyl-lysine bond, review; Review, elastase-type proteases
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Proc. 13th Eur. Pept. Symp.: Peptides 1974, 361-361 (1975)
International journal of clinical and experimental pathology, 12(4), 1260-1271 (2020-01-15)
The formation and rupture of aneurysms is a reversible process involving the destruction and repair of smooth muscle cells, and the proliferation of vascular smooth muscle cells (VSMC) and inflammation play an important role. In our study, we investigated whether
Pathologie-biologie, 36(9), 1101-1107 (1988-11-01)
Elastin in the most resistant fibrous protein of the organisms. Its degradation is catalysed by proteases designated as elastases. Elastic fibers appeared during phylogenesis at the level of the first Vertebrates and rendered possible the emergence of efficient circulatory and
Oxidative medicine and cellular longevity, 2020, 2905362-2905362 (2020-07-21)
Ultraviolet B (UVB) irradiation is major causative factor in skin aging. The aim of the present study was to investigate the protective effect of a 50% ethanol extract from Nypa fruticans (NF50E) against UVB-induced skin aging. The results indicated that
Nature communications, 13(1), 318-318 (2022-01-16)
Lung emphysema and chronic bronchitis are the two most common causes of chronic obstructive pulmonary disease. Excess macrophage elastase MMP-12, which is predominantly secreted from alveolar macrophages, is known to mediate the development of lung injury and emphysema. Here, we
Chromatograms
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