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Key Documents

138M-1

Sigma-Aldrich

CD138/syndecan-1 (B-A38) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

B-A38, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (138M-14)
vial of 0.5 mL concentrate (138M-15)
bottle of 1.0 mL predilute (138M-17)
vial of 1.0 mL concentrate (138M-16)
bottle of 7.0 mL predilute (138M-18)

manufacturer/tradename

Cell Marque

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:200

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... SDC1(6382)

General description

CD138, Syndecan 1, is a transmembrane heparan sulfate proteoglycan, present mainly in a variety of epithelial tissues, participating in cell proliferation, cell migration, intercellular communication, and cell-matrix interactions. In lymphoid tissues, CD138 is expressed in the late stages of B-cell differentiation with progression towards plasma cells. Anti-CD138 is a good marker to selectively identify plasma cells, benign or malignant, in lymphoid tissues CD138 is also expressed in a variety of epithelial cells.

Quality


IVD

IVD

IVD

RUO

Linkage

CD138/syndecan-1 Positive Control Slides, Product No. 138S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Said J, et al.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 254-254 null
A Oksanen et al.
Journal of clinical pathology, 58(4), 376-381 (2005-03-26)
Both Helicobacter pylori and gastro-oesophageal reflux disease (GORD) may cause inflammation in cardiac mucosa. Intestinal metaplasia (IM) is found more often in GORD associated inflammation than in inflammation caused by H pylori, especially in young individuals. To examine morphological differences
Said J, et al.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null
I B Bayer-Garner et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(10), 1052-1058 (2001-10-13)
Syndecan-1 (CD138) mediates myeloma cell adhesion, and loss of syndecan-1 from the cell surface may contribute to myeloma proliferation and dissemination. Flow cytometry analysis of myeloma cells in bone marrow specimens shows heterogeneity in cell surface syndecan-1 expression. It is

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