This product is soluble in water at 50 mg/ml. The solution stability of this material in water has not been determined. However, solutions diluted to 1 mg/mL may be stored in aliquots at -20°C. Avoid repeated freeze/thaw cycles.
PHR1159
Clindamycin hydrochloride
Clindamycin hydrochloride
Pharmaceutical Secondary Standard; Certified Reference Material
Sinónimos:
Clindamycin hydrochloride monohydrate, (7S)-7-Chloro-7-deoxylincomycin hydrochloride monohydrate
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About This Item
Fórmula empírica (notación de Hill):
C18H33ClN2O5S · HCl · H2O
Número de CAS:
Peso molecular:
479.46
Código UNSPSC:
41116107
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
grado
certified reference material
pharmaceutical secondary standard
Nivel de calidad
Agency
traceable to Ph. Eur. C225000
traceable to USP 1136002
familia API
clindamycin
CofA
current certificate can be downloaded
técnicas
HPLC: suitable
gas chromatography (GC): suitable
aplicaciones
pharmaceutical (small molecule)
Formato
neat
temp. de almacenamiento
-10 to -25°C
cadena SMILES
S([C@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)[C@H](NC(=O)[C@H]2[N+H](C[C@@H](C2)CCC)C)[C@@H](Cl)C)C.[Cl-].O
InChI
1S/C18H33ClN2O5S.ClH.H2O/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H;1H2/t9-,10+,11-,12+,13-,14+,15+,16+,18+;;/m0../s1
Clave InChI
KWMXKEGEOADCEQ-WNNJHRBUSA-N
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Descripción general
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Clindamycin is a common antibiotic drug generally employed for the treatment of infections caused by gram-positive aerobes and both gram-negative and gram-positive anaerobic pathogens.[1]
Clindamycin is a common antibiotic drug generally employed for the treatment of infections caused by gram-positive aerobes and both gram-negative and gram-positive anaerobic pathogens.[1]
Aplicación
Clindamycin hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography[2][1] and potentiometry[3] techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Nota de análisis
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Otras notas
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.
Nota al pie de página
To see an example of a Certificate of Analysis for this material enter LRAB7830 in the slot below. This is an example certificate only and may not be the lot that you receive.
Producto relacionado
Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Elija entre una de las versiones más recientes:
Certificados de análisis (COA)
Lot/Batch Number
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Los clientes también vieron
Liquid chromatography method for separation of clindamycin from related substances.
Orwa JA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 20(5), 745-752 (1999)
Sub-second adsorption for the fast sub-nanomolar monitoring of Clindamycin in its pure and pharmaceutical samples by fast Fourier transformation with the use of continuous cyclic voltammetry at an Au microelectrode in a flowing system
Norouzi P, et al.
Materials Science and Engineering, C, 28(1), 87-93 (2008)
John W Barlow et al.
BMC veterinary research, 9, 28-28 (2013-02-13)
Treatment of subclinical mastitis during lactation can have both direct (individual animal level) and indirect (population level) effects. With a few exceptions, prior research has focused on evaluating the direct effects of mastitis treatment, and to date no controlled field
Hui Wang et al.
Antimicrobial agents and chemotherapy, 57(3), 1538-1541 (2013-01-09)
A total of 146 group B streptococcus isolates from 8 cities across China belonged to four serotypes. Serotype Ia was more common in children. A high prevalence of resistance was observed for levofloxacin (37.7%), erythromycin (71.2%), clindamycin, (53.4%), and tetracycline
Orli Megged et al.
The Israel Medical Association journal : IMAJ, 15(1), 27-30 (2013-03-15)
Resistance to macrolides in beta-hemolytic streptococci and Streptococcus pneumoniae arises primarily due to Erm(B) or Mef(A). Erm(B) typically confers high level resistance to macrolides, lincosamides and streptogramin B (MLSB phenotype), whereas Mef(A) confers low level resistance to macrolides only (M
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Hi, when we dilute clindamycin hydrochloride PHR1159 in water, where should we store it? Thanks
1 answer-
Helpful?
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Hello! I took a look at the SDS, and found that there is no data available for clindamycin's water solubility. My team plans on purchasing this product for lab use; may I receive the information regarding clindamycin's water solubility?
1 answer-
The literature states Clindamycin hydrochloride is water soluble. The optical rotation activity is determined in water. Please note that water solubility for product number PHR1159 (Clindamycin hydrochloride) is not determined internally.
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