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M7780

Supelco

3-Methylhistamine dihydrochloride

analytical standard

Sinónimos:

3-Methyl-4-(β-aminoethyl)imidazole

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About This Item

Fórmula empírica (notación de Hill):
C6H11N3 · 2HCl
Número de CAS:
36475-47-5
Peso molecular:
198.09
MDL number:
MFCD00037002
UNSPSC Code:
41116107
PubChem Substance ID:
329817916
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.Cl.Cn1cncc1CCN

InChI

1S/C6H11N3.2ClH/c1-9-5-8-4-6(9)2-3-7;;/h4-5H,2-3,7H2,1H3;2*1H

InChI key

KWEIZIDNCJBKIY-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000380947
0000358652
0000348883
0000322195
0000358652

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J G Gerber et al.
Gastroenterology, 102(2), 403-408 (1992-02-01)
The effect of short-term intragastric arterial infusion of pentagastrin and methacholine on histamine and N tau-methyl histamine secretory rates was evaluated in mongrel dogs in vivo. Doses of pentagastrin and methacholine were chosen that stimulate gastric acid secretion equivalently. Histamine
A Sasse et al.
Journal of medicinal chemistry, 43(17), 3335-3343 (2000-09-01)
Histamine H(3)-receptor antagonists of the proxifan series are described. The novel compounds possess a 4-(3-(phenoxy)propyl)-1H-imidazole structure and various functional groups, e.g., an oxime moiety, on the phenyl ring. Synthesis of the novel compounds and X-ray crystallography of one highly potent
S O'Sullivan et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 28(11), 1332-1339 (1998-11-21)
It is generally accepted that the early asthmatic response to inhaled allergen is a result of IgE-mediated mast cell activation. In contrast, the underlying mechanism of the late asthmatic response is much less clear. In order to investigate the pattern
S Reidemeister et al.
Die Pharmazie, 55(2), 83-86 (2000-03-21)
Novel substituted N-phenylcarbamates as derivatives of 3-(1 H-imidazol-4-yl)propanol were prepared and tested for their antagonist potency in vitro and in vivo at histamine H3 receptors. Structural modifications with different alkyl and acetyl moieties were performed in an attempt to optimize
Tibor Mikó et al.
Journal of medicinal chemistry, 46(8), 1523-1530 (2003-04-04)
In an extension of very recently published studies on successful imidazole replacements in some series of histamine H(3) receptor antagonists, we report on a new class of lipophilic nonimidazole antagonist having an aliphatic tertiary amino moiety connected to a benzyl
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