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Merck
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Key Documents

ST1568

Sigma-Aldrich

Anti-DEFB4 Mouse mAb (4C4)

liquid, clone 4C4, Calbiochem®

Sinónimos:

Anti-Defensin β4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

4C4, monoclonal

form

liquid

does not contain

preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DEFB4A(1673)

General description

Purified mouse monoclonal antibody. Recognizes the DEFB4 protein.
Recognizes the DEFB4 protein.
This Anti-DEFB4 Mouse mAb (4C4) is validated for use in ELISA, Immunoblotting for the detection of DEFB4.

Immunogen

A recombinant polypeptide corresponding to amino acids 24-65 of human DEFB4, expressed as a GST fusion protein

Application


ELISA (see comments)
Immunoblotting (1-5 g/ml)

Warning

Toxicity: Regulatory Review (Z)

Physical form

In PBS, pH 7.2.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

For ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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L M Fettig et al.
Oncogene, 36(44), 6074-6084 (2017-07-12)
Half of estrogen receptor-positive breast cancers contain a subpopulation of cytokeratin 5 (CK5)-expressing cells that are therapy resistant and exhibit increased cancer stem cell (CSC) properties. We and others have demonstrated that progesterone (P4) increases CK5+ breast cancer cells. We
Olivia McGinn et al.
Oncogene, 39(12), 2478-2492 (2020-01-29)
Estrogen receptor (ER) positive breast cancers often contain subpopulations of cells that express the intermediate filament protein cytokeratin 5 (CK5). CK5+ cells are enriched in cancer stem cell (CSC) properties, can be induced by progestins, and predict poor prognosis in
Jessica Finlay-Schultz et al.
Breast cancer research : BCR, 22(1), 68-68 (2020-06-25)
Breast cancer is a highly heterogeneous disease characterized by multiple histologic and molecular subtypes. While a myriad of breast cancer cell lines have been developed over the past 60 years, estrogen receptor alpha (ER)+ disease and some mutations associated with this

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