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MAB979

Sigma-Aldrich

Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D

ascites fluid, clone 422-8D-4C-4D, Chemicon®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

ascites fluid

clon

422-8D-4C-4D, monoclonal

reactividad de especies

human

fabricante / nombre comercial

Chemicon®

técnicas

immunofluorescence: suitable

isotipo

IgG1

Condiciones de envío

wet ice

Especificidad

Reacts with Enterovirus 71. Neutralizes enterovirus 71 BrCr strain at a titer of less than 1:14.

Inmunógeno

Epitope: cross-reacts with Coxsackie A16

Aplicación

Indirect immunofluorescence at 1:1,000.

(Also cross-reacts with Coxsackie A16).

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D is validated for use in IF for the detection of Enterovirus 71.

Forma física

Ascites fluid containing no preservatives.
Unpurified

Almacenamiento y estabilidad

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
Enterovirus Control Slides, Catalogue Number 5066

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Rei-Lin Kuo et al.
PloS one, 8(5), e63431-e63431 (2013-05-08)
Induction of type-I interferons (IFNs), IFN-α/β, is crucial to innate immunity against RNA virus infection. Cytoplasmic retinoic acid-inducible gene I (RIG-I)-like receptors, including RIG-I and melanoma differentiation-associated gene 5 (MDA5), are critical pathogen sensors for activation of type-I IFN expression
Immunological and biochemical characterization of coxsackie virus A16 viral particles.
Chong, P; Guo, MS; Lin, FH; Hsiao, KN; Weng, SY; Chou, AH; Wang, JR; Hsieh, SY; Su, IJ; Liu, CC
Testing null
Elizabeth A Caine et al.
Journal of virology, 90(19), 8592-8604 (2016-07-22)
Hand, foot, and mouth disease (HFMD) has spread throughout the Asia-Pacific region, affecting millions of young children, who develop symptoms ranging from painful blisters around their mouths and hands to neurological complications. Many members of the genus Enterovirus (family Picornaviridae)
Ming-Te Yeh et al.
PloS one, 6(11), e27082-e27082 (2011-11-10)
Enterovirus 71 (EV71) has emerged as a neuroinvasive virus responsible for several large outbreaks in the Asia-Pacific region while virulence determinant remains unexplored. In this report, we investigated increased virulence of unadapted EV71 clinical isolate 237 as compared with isolate
Combining multiplex reverse transcription-PCR and a diagnostic microarray to detect and differentiate enterovirus 71 and coxsackievirus A16.
Chen, Tsan-Chi, et al.
Journal of Clinical Microbiology, 44, 2212-2219 (2006)

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