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Merck
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580549

Millipore

Tauroursodeoxycholic Acid, Sodium Salt

Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.

Sinónimos:

Tauroursodeoxycholic Acid, Sodium Salt, Sodium Tauroursodeoxycholate

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About This Item

Fórmula empírica (notación de Hill):
C26H44NO6S · Na
Número de CAS:
Peso molecular:
521.69
Número MDL:
Código UNSPSC:
12352106
NACRES:
NA.21

descripción

RTECS - KI7372500

Nivel de calidad

Ensayo

≥97% (TLC)

Formulario

solid

fabricante / nombre comercial

Calbiochem®

condiciones de almacenamiento

OK to freeze

color

white

solubilidad

water: 100 mg/mL

Condiciones de envío

ambient

temp. de almacenamiento

15-25°C

cadena SMILES

[S](=O)(=O)(O)CCNC(=O)CC[C@H]([C@@H]1[C@@]2(C(C3[C@H](C[C@H]4[C@@](C3CC2)(CC[C@H](C4)O)C)O)CC1)C)C

InChI

1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20?,21?,22+,24?,25+,26-/m1/s1

Clave InChI

BHTRKEVKTKCXOH-AYSJQVDDSA-N

Descripción general

Detergent useful for the solubilization of lipids and membrane-bound proteins. Has cryoprotective effects against hydrophobic bile salts in rats. Also reported to inhibit pepsin activity in vitro.

Aplicación


  • Inhibition of endoplasmic reticulum stress combined with activation of angiotensin-converting enzyme 2: novel approach for the prevention of endothelial dysfunction in type 1 diabetic rats.: This study highlights the efficacy of tauroursodeoxycholic acid, sodium salt in reducing endoplasmic reticulum stress, suggesting its utility in preventing vascular complications in diabetes (Gaikwad AB et al., 2022).

Advertencia

Toxicity: Standard Handling (A)

Otras notas

Ozcan, U., et al. 2006. Science313, 1137.
Miyake, H., et al. 1999. Dig. Dis. Sci.44, 197.
Eto, T. and Tompkins, R.K. 1985. Am. J. Surg.150, 564.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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