528178

Plasminogen, EACA- and Lysine-Free, Human Plasma

• Sinónimos: Plasminogen, EACA- and Lysine-Free, Human Plasma, Profibrinolysin, Plasma Trypsinogen
• Número de CAS: 9001-91-6
• Número MDL: MFCD00131922
• Código UNSPSC: 12352202
• NACRES: NA.25

Propiedades

• descripción: Merck USA index - 14, 7521
• Nivel de calidad: 100
• Formulario: lyophilized
• actividad específica: 7 units/mg protein
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: water: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Native plasminogen (EACA- and lysine-free) from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. It is converted to the active protease by cleavage at Arg⁵⁶⁰.

Advertencia

Toxicity: Irritant (B)

Definición de unidad

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Gly-Pro-Lys-pNA per min at 25°C, pH 7.8.

Forma física

Lyophilized from 20 mM sodium phosphate buffer, 10 mg D-mannitol, 10 mg NaCl.

Nota de preparación

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for at least 1 week at 4°C or for 1-2 months at -20°C.

Otras notas

Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3