09-007

Anti-acetyl STAT5B (Lys694) Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Signal transducer and activator of transcription 5B
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• species reactivity (predicted by homology): rat (based on 100% sequence homology), mouse (immunogen homology)
• technique(s): dot blot: suitable; western blot: suitable
• NCBI accession no.: NP_001107035
• UniProt accession no.: P42232
• shipped in: wet ice
• target post-translational modification: acetylation (Lys694)
• Gene Information: human ... GALNT16(57452)

Descripción

General description

STAT5B (signal transducers and activators of transcription 5b) controls the expression of early response genes and takes part in cytokine signaling. Studies have linked this protein to the inhibition of NFkappaB-mediated signaling. Additional studies have shown an association of STAT5B with regulation of lactation and growth, performance, and control of adipocyte function. Constitutively active STAT5B expression is often observed in a large number of leukemia’s and solid tumors.

Specificity

This antibody recognizes STAT5B acetylated at Lys694.

Immunogen

Epitope: Acetylated Lys694

KLH-conjugated linear peptide corresponding to mouse STAT5B acetylated at Lys694.

Application

Anti-acetyl STAT5B (Lys694) Antibody is a Rabbit Polyclonal Antibody for detection of acetyl STAT5B (Lys694) also known as Signal transducer & activator of transcription 5B & has been validated in DB & WB.

Quality

Evaluated by Dot Blot in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected STAT5B in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.

Target description

90 kDa calculated

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable