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Merck
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Key Documents

07-471

Sigma-Aldrich

Anti-Daxx Antibody

serum, Upstate®

Sinónimos:

Anti-BING2, Anti-DAP6, Anti-EAP1, Anti-SMIM40

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse, hamster

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_001350

UniProt accession no.

Q9UER7

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

hamster ... Daxx(101836409)
human ... DAXX(1616)
mouse ... Daxx(13163)
rat ... Daxx(140926)

Specificity

Daxx

Immunogen

GST fusion protein corresponding to residues 472-740 of human Daxx.

Application

Anti-Daxx Antibody is an antibody against Daxx for use in IP, WB & IC.

Quality

routinely evaluated by immunoblot in HeLa nuclear extract

Target description

110 kDa

Linkage

Replaces: 04-445

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Descripción
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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication.
Cuchet, D; Sykes, A; Nicolas, A; Orr, A; Murray, J; Sirma, H; Heeren, J; Bartelt, A; Everett, RD
Journal of Cell Science null
Sarah Müncheberg et al.
Journal of virology, 92(13) (2018-04-27)
Human adenovirus (HAdV) E1B-55K is a multifunctional regulator of productive viral replication and oncogenic transformation in nonpermissive mammalian cells. These functions depend on E1B-55K's posttranslational modification with the SUMO protein and its binding to HAdV E4orf6. Both early viral proteins
Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins.
RD Everett, C Boutell, C McNair, L Grant, A Orr
Journal of virology null
Tetsuro Komatsu et al.
Journal of virology, 90(3), 1657-1667 (2015-11-27)
Promyelocytic leukemia protein nuclear bodies (PML-NBs) are subnuclear domains implicated in cellular antiviral responses. Despite the antiviral activity, several nuclear replicating DNA viruses use the domains as deposition sites for the incoming viral genomes and/or as sites for viral DNA
Roger D Everett
Journal of virology, 90(1), 167-179 (2015-10-16)
Intrinsic immunity is an aspect of antiviral defense that operates through diverse mechanisms at the intracellular level through a wide range of constitutively expressed cellular proteins. In the case of herpesviruses, intrinsic resistance involves the repression of viral gene expression
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