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Merck
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Key Documents

06-709

Sigma-Aldrich

Anti-Gq/11α Antibody, CT

Upstate®, from rabbit

Sinónimos:

Anti-FBH, Anti-FHH2, Anti-GNA-11, Anti-HG1K, Anti-HHC2, Anti-HYPOC2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_002067
NM_002072

UniProt accession no.

P29992

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GNA11(2767)
mouse ... Gna11(14672)

Specificity

Gqα and G11α

Immunogen

peptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α

Application

Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
This Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.

Quality

routinely evaluated by immunoblot on rat brain microsomal preparation

Target description

42kDa

Physical form

Format: Purified
PBS, pH 7.4
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Referencia del producto
Descripción
Precios

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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P Cuq et al.
European journal of pharmacology, 315(2), 213-219 (1996-11-14)
The nature of the pertussis toxin-insensitive G-protein involved in muscarinic-mediated phosphoinositides breakdown and contraction of isolated smooth muscle cells from the circular layer of the rabbit caecum was investigated. Immunoblotting of membrane proteins using affinity purified antibodies directed against different
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Endocrinology, 138(8), 3299-3307 (1997-08-01)
In 3-day primary cultures of rat glomerulosa cells, a 30-min pre-incubation with either 10 microM colchicine (a microtubule-disrupting agent) or 10 microM cytochalasin B (a microfilament-disrupting agent) decreased angiotensin II (Ang II)-induced inositol phosphate accumulation by 50%. Moreover, both drugs
4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Blanc, E M, et al.
Journal of Neurochemistry, 69, 570-580 (1997)
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