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Merck

927821

Sigma-Aldrich

EBX2-alkyne

≥95%

Sinónimos:

5-Methyl-1-((trimethylsilyl)ethynyl)-1l3-benzo[d][1,2]iodaoxol-3(1H)-one

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About This Item

Fórmula empírica (notación de Hill):
C13H15IO2Si
Número de CAS:
Peso molecular:
358.25
UNSPSC Code:
12352101
NACRES:
NA.22

Quality Level

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

CC1=CC(C(OI2C#C[Si](C)(C)C)=O)=C2C=C1

Application

EBX2-alkyne is a hypervalent iodine reagent used for labeling cysteines. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitative applications . The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis . Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow .

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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