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Key Documents

926523

Sigma-Aldrich

Upconversion Nanoparticles

NaYF4,Yb,Tm@NaYF4 Yb, Nd, PEG-NH2 modified core-shell, fluorescence λex 808 nm, blue light

Sinónimos:

UCNPs

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23

Quality Level

100

concentration

2 mg/mL in water

size

30 nm ± 5%

matrix active group

PEG-NH2 surface treatment

fluorescence

λex 808 nm (blue)
λem 365 nm
λem 450 nm
λem 470 nm

storage temp.

2-8°C

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Application

Upconversion nanoparticles (ucnps), are the result of a unique optical process in which near-infrared (NIR) light excitation is converted into visible and/or UV emission. Upconversion (UC) utilizes sequential absorption of multiple photons utilizing both lifetime and real ladder-like energy levels of ions in a host lattice to produce a higher energy anti-Stokes luminescence. This optical features of UCNPs, results in deep tissue penetration and minimal autofluorescence background, for a broad range of applications of UCNP in diagnostics and biomedical imaging systems.

Applications include:
  • Fluorescent microscopy
  • Deep-tissue
  • Bioimaging
  • Nanomedicine
  • Optogenetics
  • Security labelling
  • Volumetric display

Legal Information

Product of RuixiBiotechCo. Ltd

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

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Certificados de análisis (COA)

Lot/Batch Number
MKCW1368

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Upconversion nanoparticles: design, nanochemistry, and applications in theranostics.
Guanying Chen et al.
Chemical reviews, 114(10), 5161-5214 (2014-03-13)
Shihui Wen et al.
Nature communications, 9(1), 2415-2415 (2018-06-22)
Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infra-red excitation into visible and ultraviolet emission. Their unique optical properties have advanced a broad range of applications, such as fluorescent microscopy, deep-tissue bioimaging, nanomedicine, optogenetics, security labelling and volumetric display. However
Daniel J Gargas et al.
Nature nanotechnology, 9(4), 300-305 (2014-03-19)
Imaging at the single-molecule level reveals heterogeneities that are lost in ensemble imaging experiments, but an ongoing challenge is the development of luminescent probes with the photostability, brightness and continuous emission necessary for single-molecule microscopy. Lanthanide-doped upconverting nanoparticles overcome problems
Yujia Liu et al.
Nature, 543(7644), 229-233 (2017-02-23)
Lanthanide-doped glasses and crystals are attractive for laser applications because the metastable energy levels of the trivalent lanthanide ions facilitate the establishment of population inversion and amplified stimulated emission at relatively low pump power. At the nanometre scale, lanthanide-doped upconversion
Christoph Drees et al.
Angewandte Chemie (International ed. in English), 55(38), 11668-11672 (2016-08-12)
Upconversion nanoparticles (UCNPs) convert near-infrared into visible light at much lower excitation densities than those used in classic two-photon absorption microscopy. Here, we engineered <50 nm UCNPs for application as efficient lanthanide resonance energy transfer (LRET) donors inside living cells. By

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