48640

Ethyl gallate

antioxidant, ≥96.0% (HPLC)

• Sinónimos: 3,4,5-Trihydroxybenzoic acid ethyl ester, Ethyl 3,4,5-trihydroxybenzoate, Progallin A
• Fórmula lineal: 3,4,5-(OH)₃C₆H₂COOC₂H₅
• Número de CAS: 831-61-8
• Peso molecular: 198.17
• Beilstein/REAXYS Number: 2116014
• EC Number: 212-608-5
• MDL number: MFCD00016430
• UNSPSC Code: 12352100
• PubChem Substance ID: 57651155
• NACRES: NA.22

Propiedades

• assay: ≥96.0% (HPLC)
• form: solid
• functional group: ester
• SMILES string: CCOC(=O)c1cc(O)c(O)c(O)c1
• InChI: 1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3
• InChI key: VFPFQHQNJCMNBZ-UHFFFAOYSA-N

Descripción

General description

Ethyl gallate is the ethyl ester of gallic acid that belongs to a class of phenolic compound. It is an aromatic compound that is commonly used as a starting material during the synthesis of ellagic acid via transesterification reactions.

Application

• Wound healing enhancement: Ethyl gallate, isolated from Caesalpinia mimosoides, demonstrated significant effects in promoting cutaneous wound healing. This discovery supports its potential application in therapeutic treatments for skin regeneration (Bhat et al., 2023).
• Pharmacokinetics in ethanolic extracts: A study involving ethanolic extracts of Terminalia chebula, which include ethyl gallate, detailed the pharmacokinetics of these active compounds in rats, providing critical data for pharmaceutical applications and drug development processes (Yao et al., 2023).
• Ethnopharmacology research: Research on Rubus idaeus, a source of ethyl gallate, covered extensive ethnobotany, phytochemical, and pharmacological aspects, offering insights into traditional uses and modern applications, highlighting its potential in ethnopharmacology (Tao et al., 2023).
• Dermal applications: Ethyl gallate was used in a topical ointment from Caesalpinia mimosoides to attenuate dermal wounds. This application underscores its effectiveness in skin care and treatment strategies (Bhat et al., 2022).
• Neuroprotective effects: The Jingchuan tablet, which includes ethyl gallate, has been studied for its therapeutic role in treating ischaemic cerebral stroke, focusing on the HIF-1α/EPO/VEGFA signalling pathway. This research outlines its importance in neuroprotective strategies (Zhang et al., 2022).

Ethyl gallate is utilized as a reactant in thesynthesis of quinoxalines via sustainable green chemistry process.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)