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234311

Sigma-Aldrich

Squalane

96%

Sinónimos:

2,6,10,15,19,23-Hexamethyltetracosane, Cosbiol, Perhydrosqualene, Robane

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About This Item

Fórmula lineal:
[(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2-]2
Número de CAS:
111-01-3
Peso molecular:
422.81
Beilstein/REAXYS Number:
776019
MDL number:
MFCD00008953
UNSPSC Code:
12352100
PubChem Substance ID:
24854038
NACRES:
NA.22

Quality Level

200

assay

96%

refractive index

n20/D 1.452 (lit.)

bp

176 °C/0.05 mmHg (lit.)

mp

−38 °C (lit.)

solubility

chloroform: soluble 100 mg/mL, clear

density

0.81 g/mL at 25 °C (lit.)

SMILES string

CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C

InChI

1S/C30H62/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h25-30H,9-24H2,1-8H3

InChI key

PRAKJMSDJKAYCZ-UHFFFAOYSA-N

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General description

Dielectrophoretic deformation of thin liquid fillm of squalane has been investigated. Microfluidized squalenes are efficient adjuvants, eliciting both humoral and cellular immune responses.

Application

Squalane has been used:
  • as solvent in the synthesis of Europium dibenzoylmethide triethylammonium, brightest known triboluminescent (TL) material
  • as lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

424.4 °F - closed cup

flash_point_c

218 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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A C Allison
Methods (San Diego, Calif.), 19(1), 87-93 (1999-10-20)
Microfluidized squalene or squalane emulsions are efficient adjuvants, eliciting both humoral and cellular immune responses. Microfluidization stabilizes the emulsions and allows sterilization by terminal filtration. The emulsions are stable for years at ambient temperature and can be frozen. Antigens are
Dielectrophoretic deformation of thin liquid films induced by surface charge patterns on dielectric substrates.
Berendsen CWJ, et al.
Soft Matter, 9(19), 4900-4910 (2013)
Michael Doig et al.
Langmuir : the ACS journal of surfaces and colloids, 30(1), 186-195 (2013-12-25)
The structure and friction of fatty acid surfactant films adsorbed on iron oxide surfaces lubricated by squalane are examined using large-scale molecular dynamics simulations. The structures of stearic acid and oleic acid films under static and shear conditions, and at
Alexander M Zolot et al.
The Journal of chemical physics, 129(19), 194705-194705 (2008-11-26)
Exothermic chemical reaction dynamics at the gas-liquid interface have been investigated by colliding a supersonic beam of F atoms [E(com)=0.7(3) kcalmol] with a continuously refreshed liquid hydrocarbon (squalane) surface under high vacuum conditions. Absolute HF(v,J) product densities are determined by
L Harivardhan Reddy et al.
Molecular pharmaceutics, 6(5), 1526-1535 (2009-07-29)
Gemcitabine (2',2'-difluorodeoxyribofuranosylcytosine) is an anticancer nucleoside analogue active against a wide variety of solid tumors. However, following intravenous administration, this drug is rapidly inactivated by enzymatic deamination and displays a short biological half-life necessitating the administration of high doses leading
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