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Key Documents

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219096

Sigma-Aldrich

D-Aspartic acid

99%, for peptide synthesis, ReagentPlus®

Sinónimos:

(R)-(−)-Aminosuccinic acid, (R)-2-Aminosuccinic acid

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About This Item

Fórmula lineal:
HO2CCH2CH(NH2)CO2H
Número de CAS:
1783-96-6
Peso molecular:
133.10
Beilstein/REAXYS Number:
1723529
EC Number:
217-234-6
MDL number:
MFCD00063081
UNSPSC Code:
12352209
PubChem Substance ID:
24853106
NACRES:
NA.22

product name

D-Aspartic acid, ReagentPlus®, 99%

Quality Level

100

product line

ReagentPlus®

assay

99%

form

powder

optical activity

[α]20/D −24°, c = 2.3 in 6 M HCl

optical purity

ee: 98% (GLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

application(s)

peptide synthesis

SMILES string

N[C@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1

InChI key

CKLJMWTZIZZHCS-UWTATZPHSA-N

Gene Information

rat ... Slc1a3(29483)

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Application


  • Metabolomics Analysis Identifies Differential Metabolites as Biomarkers for Acute Myocardial Infarction.: This study utilizes metabolomics to identify biomarkers for acute myocardial infarction, showcasing D-Aspartic acid′s role in amino acid metabolism and potential diagnostic applications. (Zhou et al., 2024).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
WXBF2933V
WXBF0482V
WXBD6918V
WXBD4935V
WXBD2967V

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Nobutoshi Ota et al.
Amino acids, 43(5), 1873-1886 (2012-08-09)
D-Aspartate (D-Asp) is an endogenous amino acid in the central nervous and reproductive systems of vertebrates and invertebrates. High concentrations of D-Asp are found in distinct anatomical locations, suggesting that it has specific physiological roles in animals. Many of the
Edi Erwan et al.
Amino acids, 43(5), 1969-1976 (2012-04-03)
Intracerebroventricular (i.c.v.) administration of L-aspartate (L-Asp) attenuates stress responses in neonatal chicks, but the mechanism has not been clarified. In the present study, three behavioral experiments were carried out under socially isolated stressful conditions exacerbated by the use of corticotrophin-releasing
Yuichi Kaji et al.
The British journal of ophthalmology, 96(8), 1127-1131 (2012-06-15)
Gelatinous drop-like corneal dystrophy (GDLD), also known as familial subepithelial corneal amyloidosis, is an autosomal recessive disorder that causes progressive corneal opacity due to accumulation of amyloid fibrils in the corneal stroma. Genetic analyses have revealed that a mutation in
Takehiko Yokoyama et al.
Bioscience, biotechnology, and biochemistry, 75(8), 1481-1484 (2011-08-09)
Immunohistochemical localization (cellular localization) of endogenous D-aspartate in the marine brown alga Sargassum fusiforme was investigated by the use of a specific polyclonal antibody raised against D-aspartate. D-Aspartate immunoreactivity was evident in the medullary layer in the blade of the
Akifumi Oda et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3337-3343 (2011-08-30)
Molecular dynamics simulations of amyloid β(1-42) containing D-aspartic acid residues were performed using several continuous solvent models to investigate the usefulness of simulation methods for D-amino acid-containing proteins and peptides. Normal molecular dynamics simulations and replica exchange molecular dynamics simulations
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