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146188

Sigma-Aldrich

2-Hydroxy-5-methoxybenzoic acid

98%

Sinónimos:

5-Methoxysalicylic acid

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About This Item

Fórmula lineal:
CH3OC6H3(OH)CO2H
Número de CAS:
2612-02-4
Peso molecular:
168.15
Beilstein/REAXYS Number:
2209647
EC Number:
220-037-8
MDL number:
MFCD00002459
UNSPSC Code:
12352100
PubChem Substance ID:
24848767
NACRES:
NA.22

assay

98%

form

powder

mp

141-143 °C (lit.)

functional group

carboxylic acid

SMILES string

COc1ccc(O)c(c1)C(O)=O

InChI

1S/C8H8O4/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3,(H,10,11)

InChI key

IZZIWIAOVZOBLF-UHFFFAOYSA-N

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General description

2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).

Application

2-Hydroxy-5-methoxybenzoic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

D21200

1,5-Diaminonaphthalene

Sinapic acid ≥98%, powder

Sigma-Aldrich

D7927

Sinapic acid

α-Cyano-4-hydroxycinnamic acid matrix substance for MALDI-MS, ≥99.0% (HPLC)

Supelco

70990

α-Cyano-4-hydroxycinnamic acid

T Nishihata et al.
Journal of pharmacobio-dynamics, 7(5), 278-285 (1984-05-01)
The rectal absorption of pepleomycin sulfate (PEPS) in rats was increased significantly by the coadministration with each of diclofenac (DC), sodium 5-methoxysalicylate (5-MSA) and phenylalanine enamine of ethylacetoacetate (Enamine). 5-MSA increased the lymphatic uptake of PEPS after rectal administration while
Jasmin Kemptner et al.
Rapid communications in mass spectrometry : RCM, 23(6), 877-884 (2009-02-19)
Unambiguous identification of mycotoxin-producing fungal species as Fusarium is of great relevance to agriculture and the food-producing industry as well as in medicine. Protein profiles of intact fungal spores, such as Penicillium, Aspergillus and Trichoderma, derived from matrix-assisted laser desorption/ionization
Maximilianos Kotsias et al.
PloS one, 14(1), e0210759-e0210759 (2019-01-18)
Protein O-glycosylation has shown to be critical for a wide range of biological processes, resulting in an increased interest in studying the alterations in O-glycosylation patterns of biological samples as disease biomarkers as well as for patient stratification and personalized
Cole Emanuelson et al.
SLAS discovery : advancing life sciences R & D, 26(1), 58-66 (2020-09-30)
High-throughput matrix-assisted laser desorption/ionization mass spectrometry (HT-MALDI-MS) has garnered considerable attention within the drug discovery industry as an information-rich alternative to assays using light-based detection methods. To date, these efforts have been primarily focused on assays using protein or peptide
Beatriz Gonçalves et al.
Journal of experimental botany, 68(21-22), 5801-5811 (2017-12-01)
The CUP-SHAPED COTYLEDON (CUC) transcription factors control plant boundary formation, thus allowing the emergence of novel growth axes. While the developmental roles of the CUC genes in different organs and across species are well characterized, upstream and downstream events that
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