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Key Documents

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12072

Sigma-Aldrich

Benzamidine

≥95.0%

Sinónimos:

Benzenylamidine, Phenylamidine

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About This Item

Fórmula lineal:
C6H5C(=NH)NH2
Número de CAS:
618-39-3
Peso molecular:
120.15
Beilstein/REAXYS Number:
606020
EC Number:
210-546-3
MDL number:
MFCD00042826
UNSPSC Code:
12352100
PubChem Substance ID:
57646968
NACRES:
NA.22

Quality Level

200

assay

≥95.0%

form

powder or crystals

functional group

amine
phenyl

SMILES string

NC(=N)c1ccccc1

InChI

1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)

InChI key

PXXJHWLDUBFPOL-UHFFFAOYSA-N

Gene Information

human ... F10(2159) , F2(2147) , PLAT(5327) , PLAU(5328) , PLG(5340) , PRSS1(5644)

Categorías relacionadas

Application

Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor).

Biochem/physiol Actions

Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCJ0849
BCCB9118
BCBT9196
BCBL7181V
BCBF3350V

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Purification and characterization of bovine coagulation factor XII (Hageman factor).
H Claeys et al.
European journal of biochemistry, 87(1), 69-74 (1978-06-01)
Hung-Wei Chang et al.
PLoS pathogens, 15(6), e1007826-e1007826 (2019-06-21)
Vaccinia mature virus requires A26 envelope protein to mediate acid-dependent endocytosis into HeLa cells in which we hypothesized that A26 protein functions as an acid-sensitive membrane fusion suppressor. Here, we provide evidence showing that N-terminal domain (aa1-75) of A26 protein
Ana L Roa-Espitia et al.
Biology open, 5(9), 1189-1199 (2016-07-13)
Several focal adhesion proteins are known to cooperate with integrins to link the extracellular matrix to the actin cytoskeleton; as a result, many intracellular signaling pathways are activated and several focal adhesion complexes are formed. However, how these proteins function
Use of benzamidine as a proteolytic inhibitor in the radioimmunoassay of glucagon in plasma.
J W Ensinck et al.
The Journal of clinical endocrinology and metabolism, 35(3), 463-467 (1972-09-01)
Fatma Rmili et al.
Biotechnology progress, 35(4), e2833-e2833 (2019-05-03)
A mesophilic bacterial culture, producing an extracellular alkaline lipase, was isolated from the gas-washing wastewaters generated from the Sfax phosphate plant of the Tunisian Chemical Group and identified as Staphylococcus capitis strain. The lipase, named S. capitis lipase (SCL), has
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