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Key Documents

D8517

Sigma-Aldrich

Iron–Dextran

95-105 mg/mL (Iron content), solution

Synonym(s):

Ferric hydroxide dextran complex

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

synthetic

Quality Level

sterility

aseptically filled

Assay

95-105 mg/mL (Iron content)

form

solution

contains

0.5% phenol as preservative

composition

Iron, ~100 mg/mL

color

brown

useful pH range

4 - 6.5

storage temp.

room temp

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

InChI key

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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Application

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 1B - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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I V Alenkina et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 100, 88-93 (2012-04-03)
Application of Mössbauer spectroscopy with a high velocity resolution (4096 channels) for comparative analysis of iron cores in a human liver ferritin and its pharmaceutically important models Imferon, Maltofer(®) and Ferrum Lek as well as in iron storage proteins in
V J Kumpf et al.
DICP : the annals of pharmacotherapy, 24(2), 162-166 (1990-02-01)
Parenteral iron therapy is indicated in patients with iron-deficiency anemia associated with conditions that interfere with the ingestion or absorption of oral iron. Replacement doses of iron required to replenish iron stores are based on body weight and the observed
Laura Nigi et al.
Frontiers in endocrinology, 11, 630-630 (2020-10-13)
C-X-C Motif Chemokine Ligand 10 (CXCL10) is a pro-inflammatory chemokine specifically recognized by the ligand receptor CXCR3 which is mostly expressed in T-lymphocytes. Although CXCL10 expression and secretion have been widely associated to pancreatic islets both in non-obese diabetic (NOD)
Xiao Chai et al.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 35(5), 547-552 (2013-11-05)
To establish a mouse model of iron overload by intraperitoneal injection of iron dextran and investigate the impact of iron overload on bone marrow hematopoiesis. A total of 40 C57BL/6 mice were divided into control group, low-dose iron group (12.5
S Fishbane et al.
Seminars in dialysis, 13(6), 381-384 (2000-12-29)
Intravenous iron treatment is an important component of anemia therapy for patients on dialysis. Until recently iron dextran was the only parenteral form of iron available in the United States. This drug has been associated with occasional serious adverse reactions

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