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Key Documents

ALD00062

Sigma-Aldrich

2,5-Difluorobenzenesulfonyl fluoride

95%

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About This Item

Empirical Formula (Hill Notation):
C6H3F3O2S
CAS Number:
Molecular Weight:
196.15
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

form

solid

reaction suitability

reaction type: click chemistry

mp

30-36 °C

SMILES string

FS(C1=C(F)C=CC(F)=C1)(=O)=O

InChI

1S/C6H3F3O2S/c7-4-1-2-5(8)6(3-4)12(9,10)11/h1-3H

InChI key

QHGFXAZDLIJQIV-UHFFFAOYSA-N

Application

Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic
acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and phosphate groups as linkers.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

216.0 °F

Flash Point(C)

102.22 °C


Certificates of Analysis (COA)

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Articles

In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

Related Content

The Sharpless Lab pursues useful new reactivity and general methods for selectively controlling chemical reactions.

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