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921483

Sigma-Aldrich

Droplet generation and storage chip

Fluidic 719, PC

Synonym(s):

Microfluidic, Microparticle, Nanoparticle

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About This Item

UNSPSC Code:
42142600
NACRES:
NA.23

description

Microfludic chip x1

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Application

Microfluidic generation of droplets can produce highly monodispersed droplets with high frequency (up to hundreds of kHz). Interest in droplet-based microfluidic systems has grown substantially, because microfluidics offers the ability to handle very small volumes (μl to fl) of fluids, provides better mixing, encapsulation, sorting, and sensing. Microfluidics can be used for high throughput experimentation. Microfluidic-based droplets have many diverse and varied applications such as particle synthesis and chemical analysis. Highly controlled droplet production also makes single cell analysis, or drug testing possible.
Droplet generation and storage chip, Fluidic 719, PC is made of PC (polycarbonate), and has a storage channel design, which can be used for optical analysis. The channel design of Fluidic 719 has an additional flow focusing junction and droplet storage is realized in one channel, rather than in rhombic units. The chip contains 2261 storage positions and can be used for a wide-range of applications including droplet-based cell culture/monitoring.

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Recent advances of controlled drug delivery using microfluidic platforms.
Li X, et al.
Drug delivery, 128, 3-28 (2018)
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range
Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired

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Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

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