56951

N-(2-Aminoethyl)maleimide trifluoroacetate salt

≥98% (T), for peptide synthesis

• Synonym(s): 2-Maleimidoethylamine trifluoroacetate salt
• Empirical Formula (Hill Notation): C₆H₈N₂O₂ · C₂HF₃O₂
• CAS Number: 146474-00-2
• Molecular Weight: 254.16
• MDL number: MFCD01073617
• UNSPSC Code: 12161502
• PubChem Substance ID: 57651612
• NACRES: NA.22

Properties

• product name: N-(2-Aminoethyl)maleimide trifluoroacetate salt, ≥95% (HPLC), ≥98% (T)
• Assay: ≥95% (HPLC); ≥98% (T)
• form: powder
• reaction suitability: reagent type: cross-linking reagent; reagent type: linker
• functional group: amine; maleimide
• polymer architecture: functionality: heterobifunctional
• SMILES string: OC(C(F)(F)F)=O.O=C1N(CCN)C(C=C1)=O
• InChI: 1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)
• InChI key: YNHKVOGCDPODMT-UHFFFAOYSA-N

Description

General description

N-(2-Aminoethyl)maleimide trifluoroacetate salt is a thiol reactive cross-linking agent used in the preparation of heparin hydrogels

Application

N-(2-Aminoethyl)maleimide trifluoroacetate salt commonly utilized:

• As a crosslinking agent to form covalent bonds between polymeric precursors
• In the synthesis of maleimide-functionalized heparin hydrogels by introducing maleimide functional groups to molecules, enabling subsequent bioconjugation
• In the synthesis of N-(2-{3-Iodobenzoyl}aminoethyl)maleimide and N-(2-{3-(tri-n-Butylstannyl)benzoyl}aminoethyl)maleimide
• As a building block in the synthesis of maleimide-functionalized cymantrenyl derivatives

Other Notes

Heterobifunctional linker for introducing a maleimide function into the widely used NOSu-modified fluorescent labels.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves