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Synthesis of the cyclohexane core of phomactins and a new route to the bicyclo[9.3.1]pentadecane diterpenoid skeleton.

Organic letters (2010-12-18)
Keith D Schwartz, James D White
RESUMEN

Conjugate reduction of an enone accompanied by in situ intramolecular aldol condensation was used to construct the tetrasubstituted cyclohexane nucleus of phomactins. Subsequent relay ring-closing metathesis completed the nine-membered ansa bridge of the diterpenoid framework.

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Sigma-Aldrich
Pentadecane, ≥99%
Sigma-Aldrich
Pentadecane, ≥98.0% (GC)
Supelco
Pentadecane, analytical standard