Carbazole is an aromatic heterocyclic organic molecule.
Application
Carbazole has been used in the uronic acid assay.[1]
Biochem/physiol Actions
Carbazole mainly interacts with DNA and damages it. These events suppress the synthesis of new DNA or RNA. Carbazole derivatives are involved in antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidant, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective, and pancreatic lipase suppression activities.
A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices.
Tranchepain F, et al.
Analytical Biochemistry, 348, 232-242 (2006)
CARBAZOLE DERIVATIVES IN CANCER TREATMENT-A REVIEW.
Kanneti Naga M, et al.
World Journal of Pharmacy and Pharmaceutical Sciences (2015)
Advanced materials (Deerfield Beach, Fla.), 24(21), 2911-2915 (2012-05-03)
A new carbazole derivative with two carbazole moieties on the C3 and C6 positions of carbazole and triphenylsilane directly linked to the N of carbazole is successfully used as a highly efficient blue phosphorescent host in an organic light-emitting diode
The racemic modification of the Aspidosperma alkaloid limaspermidine (1) has been prepared in ten steps including one involving a Raney-cobalt-mediated tandem reductive cyclization of nitrile 8 to give the tetracyclic system 9b. Compound (±)-1 has been converted over two steps
Journal of medicinal chemistry, 53(13), 5054-5058 (2010-06-05)
Mitotic kinesin spindle protein (KSP) is involved in the assembly of the bipolar spindle during cell division. On the basis of a common 2,3-fused indole substructure within the complex frameworks of terpendole E and other KSP inhibitors, the carbazoles with
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