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Sigma-Aldrich

Sodium deoxycholate monohydrate

BioUltra, ≥99.0% (NT)

Synonym(s):

3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C24H39NaO4 · H2O
CAS Number:
145224-92-6
Molecular Weight:
432.57
Beilstein:
3643164
EC Number:
206-132-7
MDL number:
MFCD00150750
UNSPSC Code:
12161900
PubChem Substance ID:
57648496
NACRES:
NA.25

description

anionic

Quality Level

300

product line

BioUltra

Assay

≥99.0% (NT)

form

powder

optical activity

[α]20/D +44±2°, c = 2% in H2O

mol wt

average mol wt 1200-5000

aggregation number

3-12

impurities

insoluble matter, passes filter test
≤0.5% cholic acid (TLC)
≤6.1% water

pH

7.5-9.5 (25 °C, 0.1 M in H2O)

CMC

2-6

solubility

H2O: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Al: ≤20 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
Li: ≤5 mg/kg
Mg: ≤20 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤20 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in H2O

UV absorption

λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08

HLB

16

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O4.Na.H2O/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);;1H2/q;+1;/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;;/m1../s1

InChI key

NDVHNZISGVSFMP-WTCAICSISA-M

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General description

Sodium deoxycholate monohydrate is a lipid bile salt used in drug delivery systems.

Application

Powerful solubilization agent; used in the solubilization of estrogen synthetase from human placental microsomes.

Biochem/physiol Actions

Bile salt

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Skeletal muscle preservation is a dynamic process that involves constant repair and regeneration. However, the regenerative capacity of muscle cells declines in hyperglycemia. This study aimed to explore the molecular mechanisms underlying this glucotoxicity during myoblast differentiation. C2C12 cells were exposed

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