This product is lyophilized from a solution containing 20 mM Tris-HCl, 2 mM EDTA, pH 7.5. The product may be reconstituted in water. Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
528175
Plasminogen, Human Plasma
Synonym(s):
Plasminogen, Human Plasma, Profibrinolysin, Plasma Trypsinogen
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About This Item
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biological source
human plasma
Quality Level
description
Merck USA index - 14, 7521
Assay
≥95% (SDS-PAGE)
form
lyophilized
specific activity
≥120 units/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: soluble
shipped in
ambient
storage temp.
−20°C
General description
Native plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.
Native plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg560.
Warning
Toxicity: Irritant (B)
Unit Definition
One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
Physical form
Lyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.
Preparation Note
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
Other Notes
Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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