The heat inactivation of esterases in human and rabbit serum was followed at 50 and 55 degrees C by measuring the decrease of activity with paraoxon, phenylacetate and beta-naphthylacetate as substrates. The rate of inactivation measured with the three substrates
Xenobiotica; the fate of foreign compounds in biological systems, 17(7), 815-821 (1987-07-01)
The patterns of metabolic conjugation of the isomeric 1- and 2-naphthylacetic acids have been compared in guinea pig, mouse, hamster and gerbil. Equimolar doses of [carboxy-14C]1- and 2-naphthylacetic acids were given to these species by i.p. injection, their urine collected
Xenobiotica; the fate of foreign compounds in biological systems, 13(3), 133-138 (1983-03-01)
Although the occurrence of the taurine conjugation mechanism for various xenobiotic acids is well established, nothing is known of the source of the taurine used for this conjugation. [14C]Taurine was administered alone and in combination with 2-naphthylacetic acid or clofibric
[reaction: see text] 6(A),6(D)-Bispyridinio-appended gamma-cyclodextrin effectively enhanced the excimer fluorescence of 2-naphthylacetate. This increase derived from the increase of formation of the 1:2 complex between the cation-charged gamma-cyclodextrin and 2-naphthylacetate by the electrostatic interaction between the host and the guest.
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