412368

PAMAM dendrimer

ethylenediamine core, generation 0.0 solution, 20 wt. % in methanol

• Synonym(s): Poly(amidoamine)
• Linear Formula: NH₂(CH₂)₂NH₂]:(G=0);dendri PAMAM(NH₂)₄
• CAS Number: 155773-72-1
• Molecular Weight: 516.68
• MDL number: MFCD00192446
• UNSPSC Code: 12162002
• PubChem Substance ID: 24865805
• NACRES: NA.23

Properties

• description: amino surface groups
• form: liquid
• mol wt: generation 0.0
• feature: core type ethylenediamine core (2-carbon core)
• concentration: 20 wt. % in methanol
• no. Surface Groups: 4
• refractive index: n20/D 1.364
• bp: 64.7 °C
• density: 0.854 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: NCCNC(=O)CCN(CCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN
• InChI: 1S/C22H48N10O4/c23-5-9-27-19(33)1-13-31(14-2-20(34)28-10-6-24)17-18-32(15-3-21(35)29-11-7-25)16-4-22(36)30-12-8-26/h1-18,23-26H2,(H,27,33)(H,28,34)(H,29,35)(H,30,36)
• InChI key: SENLDUJVTGGYIH-UHFFFAOYSA-N

Description

General description

PAMAM dendrimer is a poly(amidoamine) that is categorized under the class of dendritic polymers, which can be prepared by a two-step reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular branched upon branched pattern. PAMAM is majorly used as a high capacity chelating agent.

Application

PAMAM dendrimer belongs to the family of dendrimers, which can be used in biomedical and drug delivery applications.

Physical form

Contains 4 surface primary amino groups

Legal Information

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup