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320617

Sigma-Aldrich

Ethyl 4-hydroxy-3-methoxycinnamate

98%

Synonym(s):

Ethyl ferulate

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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2C2H5
CAS Number:
4046-02-0
Molecular Weight:
222.24
EC Number:
223-745-5
MDL number:
MFCD00009190
UNSPSC Code:
12352100
PubChem Substance ID:
24859274
NACRES:
NA.22

Assay

98%

form

solid

bp

164-166 °C/0.5 mmHg (lit.)

mp

63-65 °C (lit.)

SMILES string

CCOC(=O)\C=C\c1ccc(O)c(OC)c1

InChI

1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+

InChI key

ATJVZXXHKSYELS-FNORWQNLSA-N

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kin Kwan Lai et al.
Applied and environmental microbiology, 75(15), 5018-5024 (2009-06-09)
Cinnamic acids (i.e., ferulic and caffeic acids) that are esterified to the vegetable cell walls should be enzymatically released to be absorbed in a mammal's intestines. A low dosage of ferulic acid in rodent diets stimulates insulin production and alleviates
Marzia Perluigi et al.
Journal of neuroscience research, 84(2), 418-426 (2006-04-25)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of amyloid-beta peptide (Abeta), a peptide that as both oligomers and fibrils is believed to play a central role in the development and progress of AD by inducing oxidative
Giovanni Scapagnini et al.
Advances in experimental medicine and biology, 698, 27-35 (2010-01-01)
In recent years there has been a growing interest, supported by a large number of experimental and epidemiological studies, in the beneficial effects of some commonly used food-derived products in preventingvarious age-related pathologic conditions, ranging from cancer to neurodegenerative diseases.
Rukhsana Sultana et al.
Journal of neurochemistry, 92(4), 749-758 (2005-02-03)
Alzheimer's disease (AD) is neuropathologically characterized by depositions of extracellular amyloid and intracellular neurofibrillary tangles, associated with loss of neurons in the brain. Amyloid beta-peptide (Abeta) is the major component of senile plaques and is considered to have a causal
Aiping Zhang et al.
Planta, 229(5), 1099-1108 (2009-02-24)
Radical coupling reactions between ethyl ferulate (Et-FA), a simple model for feruloyl polysaccharides in planta, and coniferyl alcohol (CA), a monolignol, were studied in order to better understand the polymer cross-coupling interactions among polysaccharides and monolignols or lignin, mediated by
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