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1046205

USP

Aztreonam

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

[2S-[2α,3β(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid

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About This Item

Formule empirique (notation de Hill):
C13H17N5O8S2
Numéro CAS:
78110-38-0
Poids moléculaire :
435.43
Numéro MDL:
MFCD00072145
Code UNSPSC :
41116107
ID de substance PubChem :
329749093
Nomenclature NACRES :
NA.24
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Qualité

pharmaceutical primary standard

Famille d'API

aztreonam

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

C[C@H]1[C@H](NC(=O)\C(=N/OC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O

InChI

1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

Clé InChI

WZPBZJONDBGPKJ-VEHQQRBSSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aztreonam USP reference standard is meant to use for specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay according to the given below monographs of United States Pharmacopeia (USP):
  • Aztreonam[1]
  • Aztreonam for Injection[2]
  • Aztreonam Injection[3]

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Aztreonam for Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 463-463 (2018)
Aztreonam Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 462-462 (2018)
Michael N Dudley et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(9), 1301-1309 (2013-01-22)
Widespread resistance in Enterobacteriaceae and Pseudomonas aeruginosa to cephalosporin and monobactam antibiotics due to extended-spectrum β-lactamases (ESBLs) has resulted in the need for reassessment of the interpretative criteria (breakpoints) established for these agents more than 2 decades ago. Following extensive
Stéphanie Nemeghaire et al.
The Journal of antimicrobial chemotherapy, 69(11), 2928-2934 (2014-07-27)
This study aimed at assessing the epidemiology and genetic diversity of methicillin-resistant Staphylococcus sciuri (MRSS) from different farm animal species. Nasal swabs were collected from 200 pigs, 100 dairy cows, 100 beef cows, 150 veal calves and 200 broilers. Colonies
Kristen Zeitler et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 69(2), 107-115 (2012-01-05)
The pharmacology, safety, efficacy, pharmacokinetics, pharmacodynamics, current place in therapy, and potential future therapeutic uses of inhaled aztreonam are reviewed. Inhaled aztreonam, a newly formulated lysine salt of the original monobactam antibiotic, is approved for the treatment of respiratory symptoms
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Questions

  1. quelle est la solubilité de ce produit et ds quel solvant et eau ? Merci

    1 answer

    1. This is a product of the United States Pharmacopeia. Solubility testing has not been performed. However, the research product A6848 is tested for solubility at 50 mg/ml in a 1:1 mixture of dimethylformamide and methanol. Another research grade item, PZ0038, is tested for solubility at 2 mg/mL in DMSO. The solubility in water has not been determined.

      Please see the link below to review the datasheet for the research grade material, A6848:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/320/622/a6848pis.pdf

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