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Discovery® C18 (5 µm) HPLC Columns

L × I.D. 25 cm × 10 mm, HPLC Column

Synonyme(s) :

Discovery RP18 HPLC Column

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About This Item

Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52

product name

Colonne HPLC Discovery® C18, 5 μm particle size, L × I.D. 25 cm × 10 mm

Matériaux

stainless steel column

Agence

suitable for USP L1

Gamme de produits

Discovery®

Caractéristiques

endcapped

Fabricant/nom de marque

Discovery®

Conditionnement

1 ea of

Ampleur du marquage

12% Carbon loading

Paramètres

≤70 °C temp. range
400 bar pressure (5801 psi)

Technique(s)

HPLC: suitable
LC/MS: suitable

L × D.I.

25 cm × 10 mm

Superficie

300 m2/g

Couverture de surface

3 μmol/m2

Impuretés

<10 ppm metals

Matrice

silica gel, high purity, spherical particle platform
fully porous particle

Groupe de la matrice active

C18 (octadecyl) phase

Taille des particules

5 μm

Dimension de pores

180 Å

operating pH range

2-8

Application(s)

food and beverages

Technique de séparation

reversed phase

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Description générale

Utilisez les colonnes Discovery® C18 pour toutes les méthodes qui demandent une colonne C18. La forme exceptionnelle des pics, la reproductibilité et la stabilité en font la colonne de choix pour toutes les méthodes C18, des applications de routines à celles les plus exigeantes.

Application


  • Development and Validation of a Reversed-Phase HPLC Method with UV Detection for the Determination of L-Dopa in Vicia faba L. Broad Beans.: Highlights the application of the Discovery® C18 HPLC Column in developing a method for the accurate quantification of L-Dopa in natural sources, which is essential for studies in neuropharmacology and natural product research (Tesoro et al., 2022).

  • Simultaneous estimation of paclitaxel and erlotinib in plasma by liquid chromatography/(+) electrospray tandem mass spectrometry: application in formulation development and pharmacokinetics.: This study employs the Discovery® C18 HPLC Column to enhance the simultaneous analysis of paclitaxel and erlotinib, critical for cancer therapy research and formulation development (Khuroo et al., 2022).

Caractéristiques et avantages

  • Reproductibilité excellente
  • Forme exceptionnelle des pics des analytes basiques et acides
  • Séparations LC-MS stables à faible diffusion
  • Séparation des peptides et petites protéines
  • Hydrophobicité moindre que celle de nombreuses colonnes comparables, produisant une analyse plus rapide

Produits recommandés

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Informations légales

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Yoshinori Masukawa et al.
Journal of lipid research, 49(7), 1466-1476 (2008-03-25)
Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species might be closely related to the regulation of keratinization, together with other CER-related lipids. Structures of those diverse
Pei Yuan et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(42), 11319-11325 (2009-09-18)
This study systematically investigates periodic mesoporous organosilicas (PMOs) with controlled helical and concentric circular (CC) pore architectures prepared through a basic-catalyzed sol-gel process by using an achiral cationic surfactant trimethyloctadecylammonium bromide (C(18)TAB) as a structure-directing agent, perfluorooctanoic acid (PFOA) as
R Nageswara Rao et al.
Biomedical chromatography : BMC, 23(11), 1145-1150 (2009-05-16)
A highly sensitive and selective on-line two-dimensional reversed-phase liquid chromatography/electrospray ionization-tandem mass spectrometry (2D-LC-ESI/MS/MS) method was developed and validated to determine rifaximin in rat serum by direct injection. The 2D-LC-ESI/MS/MS system consisted of a restricted access media column for trapping
Pilar Heredia-Middleton et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 149(4), 552-556 (2008-02-01)
Heat shock protein 70 (HSP70, 70 kDa) is the most commonly expressed protein in response to thermal stress. The extent of its expression is associated with differences in environmental temperatures. We investigated the heat shock response in red blood cells
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of

Contenu apparenté

Discovery C18 and C8 HPLC Columns products offered

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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